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Schwannoma is a benign nerve sheath tumor arising from differentiated schwann cells The integration of clinical, histological, and immunohistochemical findings is crucial for distinguishing schwannoma from other nerve sheath tumors. There are a few morphologically distinct variants of schwannomas, in addition to the conventional schwannoma, which are discussed later
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Cellular schwannoma cellular schwannomas have a higher cellularity and mitotic rate than conventional schwannomas, and may be locally erosive but are benign tumors without metastatic potential. Understanding schwannoma pathology is essential for accurate diagnosis and effective management Schwannoma is also known as an “neurilemmoma”, “neurolemmoma”, and “schwann cell tumour ”
It is a benign peripheral nerve sheath tumour composed of schwann cells
Schwann cells normally produce the insulating myelin sheath covering peripheral nerves Schwannoma is a relatively common peripheral nerve sheath tumour At the cerebellopontine (cp) angle, they may be referred to as acoustic neuroma or vestibular schwannoma. Schwannomas, less commonly called neurinomas or neurilemmomas, are benign tumors of schwann cell origin and are the most common tumor of peripheral nerves, including cranial nerves
This article provides a general overview of schwannomas The tumour is made up of specialized nerve cells called schwann cells This tumour can occur at any age and in any location in the body. The remainder are associated with neurofibromatosis 2 (3%), schwannomatosis (2%), or multiple meningiomas with or without nf2 (5%)
Schwannomas may rarely arise in the setting of nf1
The most common locations are head, neck, upper and lower extremities, posterior.
