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What is the concern about biotin interference with clinical laboratory assays The fda warns that taking too much biotin can interfere with lab tests, such as hormone tests and tests for markers of heart attacks (like troponin). Biotin supplements, when taken in high doses, can cause interference with certain immunoassays.
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Fda has updated its safety communication to remind the public that biotin, also known as vitamin b7, often found in dietary supplements, can significantly interfere with certain lab tests,. But biotin supplements may contain up to 650 times the adequate intake The level of biotin in the blood is highest about 1 to 3 hours after taking a dose
Biotin can affect your lab results for hours to days after taking a dose, depending on these factors.
While the amount of biotin naturally received through dietary means is not enough to interfere with clinical tests, the levels found in these supplements can generate significant errors A wide variety of laboratory tests rely on biotin as a component of the assay. Research shows that even a single 10 milligram (10,000 mcg) dose of biotin can interfere with thyroid function tests conducted within 24 hours of taking the supplement For example, a small study among six healthy adults taking 10,000 mcg of biotin per day for one week experienced lab interferences that could have drastic consequences.
“because biotin can interfere with lab tests, it can lead to misdiagnosis or inappropriate management of medical conditions,” dr The typical recommendation is to stop taking biotin at least 72 hours before having tests done. Patients on high dose biotin may see their immunoassay results affected by biotin Biotin interference can give falsely high or falsely low results depending on the design of the particular immunoassay.
The fda recommends stopping biotin consumption at least 72 hours before blood tests [5]
To ensure the accuracy of blood test results, patients should temporarily stop taking biotin supplements before a blood draw
