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During acute flares, it may be necessary to increase the dose by 25 mg or 50 mg daily Your dose needs may change if you switch to a different brand, strength, or form of indomethacin. Doses above 150 mg to 200 mg once a day generally do not increase the effectiveness of this drug.
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Adults—25 milligrams (mg) two or three times a day Use the lowest dose that is effective in treating your condition Your doctor may increase your dose by 25 or 50 mg per day, as needed
However, the total dose is usually not more than 200 mg per day
Children 15 years of age and older—dose is based on body weight and must be determined by your doctor. Indomethacin suppositories only come in one dosage (50 mg), so the dosing may vary slightly Typically, you can use one indomethacin suppository 2 to 4 times per day. Use lowest effective dose for shortest duration
Following single oral doses of indomethacin capsules 25 mg or 50 mg, indomethacin is readily absorbed, attaining peak plasma concentrations of about 1 and 2 mcg/ml, respectively, at about 2 hours. Very few drugs come in a fixed dose or a single dose Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
